Saturday, June 8, 2024

1 in 6 Who Stop Antidepressants Experience Discontinuation Symptoms, Analysis Finds

https://alert.psychnews.org/2024/06/1-in-6-who-stop-antidepressants.html


About 1 in 6 individuals who stop taking their antidepressant experience at least one withdrawal symptom such as dizziness, headache, insomnia, or irritability, according to the results of a study published yesterday in Lancet Psychiatry. About 1 in 33 individuals experience severe withdrawal symptoms such that they would drop out of a clinical trial or restart their antidepressant.


Some findings related to specific medications were as follows:

  • Desvenlafaxine, venlafaxine, imipramine, and escitalopram were associated with a higher frequency of symptoms.
  • Desvenlafaxine, venlafaxine, imipramine, and paroxetine were associated with a higher severity of symptoms.