Precision psychiatry, which tailors mental health treatment based on individual biological differences, has achieved several significant milestones over the past decade:
1. **Biotyping and Personalized Treatment**: Researchers at Stanford University have developed methods to categorize patients with depression and anxiety into specific biotypes using functional MRI scans. This allows clinicians to bypass ineffective treatments and directly offer therapies that are more likely to work for each patient's unique brain circuitry [oai_citation:1,Finding personalized approaches to treating mental illness](https://stanmed.stanford.edu/precision-mental-health-promise/) [oai_citation:2,Designing psychiatric care to precisely match patients' biology - Scope](https://scopeblog.stanford.edu/2021/12/16/designing-psychiatric-care-to-precisely-match-patients-biology/).
2. **Personalized Transcranial Magnetic Stimulation (TMS)**: Advances in TMS have enabled personalized targeting of brain areas based on individual functional connectivity. This approach has shown improved treatment efficacy and safety by focusing magnetic stimulation on precisely identified neural targets [oai_citation:3,Personalized TMS for Psychiatric Disorders: Targeting Functional Connectivity (FC) in the Brain (2024 Review) - MentalHealthDaily](https://mentalhealthdaily.com/2024/03/05/personalized-tms-psychiatric-disorders-functional-connectivity-brain-2024-review/).
3. **Predictive Models and Digital Approaches**: Precision psychiatry has also integrated machine learning models to predict treatment responses and relapse risks. Digital tools, including passive and active data collection methods like smartphone usage patterns and experience sampling, are being used to gather real-time data, enhancing the ecological validity of assessments [oai_citation:4,The potential of precision psychiatry: what is in reach? | The British Journal of Psychiatry | Cambridge Core](https://www.cambridge.org/core/journals/the-british-journal-of-psychiatry/article/potential-of-precision-psychiatry-what-is-in-reach/20BEF37FD2062468AF0E3C23A0B6F6FE).
4. **Integration of Advanced Neuroimaging**: By combining clinical data with advanced neuroimaging and computational models, researchers have identified subgroups within psychiatric disorders that respond differently to various treatments. This stratification helps in developing targeted therapies, improving overall treatment outcomes [oai_citation:5,The potential of precision psychiatry: what is in reach? | The British Journal of Psychiatry | Cambridge Core](https://www.cambridge.org/core/journals/the-british-journal-of-psychiatry/article/potential-of-precision-psychiatry-what-is-in-reach/20BEF37FD2062468AF0E3C23A0B6F6FE).
5. **Development of New Therapies**: The insights gained from precision psychiatry have led to the exploration and development of novel treatment options, including both pharmacological and non-pharmacological interventions, tailored to the specific needs of patients based on their biotypes [oai_citation:6,Finding personalized approaches to treating mental illness](https://stanmed.stanford.edu/precision-mental-health-promise/) [oai_citation:7,Designing psychiatric care to precisely match patients' biology - Scope](https://scopeblog.stanford.edu/2021/12/16/designing-psychiatric-care-to-precisely-match-patients-biology/).
These advancements underscore the potential of precision psychiatry to transform mental health care by providing more effective, personalized treatments and improving the lives of those with psychiatric conditions.
