Safranski's most popular works are monographs on Friedrich Schiller, E.T.A. Hoffmann, Arthur Schopenhauer, Friedrich Nietzsche, Martin Heidegger, and Johann Wolfgang von Goethe.
From 2002 to 2012, he co-hosted (along with Peter Sloterdijk) a bi-monthly debate on philosophical and ethical questions, the so-called "Philosophical Quartet" (German: Philosophisches Quartett), for German public-service TV station ZDF.