Sunday, April 28, 2024

Telomere (TTAGGG)

端粒(英語:Telomere)是真核生物染色體末端的DNA重複序列,作用是保持染色體的完整性和控制細胞分裂週期。 

In 1975–1977, Elizabeth Blackburn (b 1948), working as a postdoctoral fellow at Yale University with Joseph G. Gall, discovered the unusual nature of telomeres, with their simple repeated DNA sequences composing chromosome ends.[6] Blackburn, Carol Greider, and Jack Szostak were awarded the 2009 Nobel Prize in Physiology or Medicine for the discovery of how chromosomes are protected by telomeres and the enzyme telomerase.[7]


Blackburn was appointed a member of the President's Council on Bioethics in 2002.[21] She supported human embryonic cell research, in opposition to the Bush administration. Her Council terms were terminated by White House directive on 27 February 2004.[22] Dr. Blackburn believes that she was dismissed from the Council due to her disapproval of the Bush administration's position against stem cell research.[23


https://en.wikipedia.org/wiki/Telomere

https://www.toolsbiotech.com/news_detail.php?id=157

https://geneonline.news/telomere-aging/

https://www.airitilibrary.com/Article/Detail/18164749-200310-201209100026-201209100026-837-841

Telomeres and Telomere Length: A General Overview