Saturday, July 20, 2024

Evolutionary Developmental Biology (Evo-Devo): Past, Present, and Future (2012) (negativity vs vitality)

https://evolution-outreach.biomedcentral.com/articles/10.1007/s12052-012-0418-x

https://en.wikipedia.org/wiki/Evolutionary_developmental_biology


演化發育生物學 (evo-devo)

The field is composed of multiple core evolutionary concepts. One is deep homology, the finding that dissimilar organs such as the eyes of insectsvertebrates and cephalopod molluscs, long thought to have evolved separately, are controlled by similar genes such as pax-6, from the evo-devo gene toolkit. These genes are ancient, being highly conserved among phyla; they generate the patterns in time and space which shape the embryo, and ultimately form the body plan of the organism. Another is that species do not differ much in their structural genes, such as those coding for enzymes; what does differ is the way that gene expression is regulated by the toolkit genes. These genes are reused, unchanged, many times in different parts of the embryo and at different stages of development, forming a complex cascade of control, switching other regulatory genes as well as structural genes on and off in a precise pattern. This multiple pleiotropic reuse explains why these genes are highly conserved, as any change would have many adverse consequences which natural selection would oppose


Deep homology (深度同源性)


Evo-devo gene toolkit (Toolkit genes) (工具包基因)