https://alert.psychnews.org/2024/04/generic-drug-combination-cuts-drinking.html
“Considering the small number of approved medications and current limited use of pharmacotherapy for AUD, all with limited-to-moderate efficacy, patients with AUD as well as their physicians [need] additional treatments,” wrote lead author Henri-Jean Aubin of the Université Paris-Saclay in Villejuif, France, and colleagues.
Aubin and colleagues suggested that cyproheptadine, an anti-allergic medication, and prazosin, which treats hypertension and urinary urgency, might work well together. The former targets receptors involved in impulsive behaviors, and the latter targets receptors related to cravings.